#NEXUS 
begin data;
	dimensions ntax=6 nchar=4592;
	format datatype=protein interleave gap=-
		   symbols="12" equate="S={12}";
	options gapmode=newstate;

MATRIX

[Aldolase]

Arabidopsis       MS----AFVSKYEDELIKTAKYIATPGRGILAADESTETIGKRFAGINVENTESNRQAYR
Schistosoma       MSRFQPYLTEAQENDLRRIAQAICAPGKGILAADESTATMGKRLQQIGVENNEENRRLYR
Caenorhabditis    MASYSQFLTKAQEDELRSIANAIVTPGKGILAADESTGSMDKRLNSIGLENTEENRRKYR
Drosophila        MTTYFNYPSKELQDELREIAQKIVAPGKGILAADESGPTMGKRLQDIGVENTEDNRRAYR
Mus               MPHPYPALTPEQKKELSDIAHRIVAPGKGILAADESTGSIAKRLQSIGTENTEENRRFYR
Homo              MPYQYPALTPEQKKELSDIAHRIVAPGKGILAADESTGSIAKRLQSIGTENTEENRRFYR

Arabidopsis       ELLFTSPGSY-PCLSGVILFEETLYQKTSDGKPFVDLLMENGVIPGIKVDKGLVDLAGTN
Schistosoma       QLLFSADHKLAENISGVILFEETLHQKSDDGKTLPTLLAERNIIPGIKVDKGVVPLAGTD
Caenorhabditis    QLLFTAGADLNKYISGVIMFHETFYQKTDDGKPFTALLQEQGIIPGIKVDKGVVPMAGTI
Drosophila        QLLFSTDPKLAENISGVILFHETLYQKADDGTPFAEILKKKGIILGIKVDKGVVPLFGSE
Mus               QLLLTADDRVNPCIGGVILFHETLYQKADDGRPFPQVIKSKGGVVGIKVDKGVVPLAGTN
Homo              QLLLTADDRVNPCIGGVILFHETLYQKADDGRPFPQVIKSKGGVVGIKVDKGVVPLAGTN

Arabidopsis       GETTTQGLDSLGARCQQYYEAGGRFAKWRAFFKIGATEPSVLSIQEDA-RVLARYAIICQ
Schistosoma       NETTTQGLDDLASRCAEYWRLGCRFAKWRCVLKISSHTPSYLAMLENA-NVLARYASICQ
Caenorhabditis    GEGTTQGLDDLNARCAQYKKDGAQFAKWRCVHKISSTTPSVTALKEIASNLGSRYASICQ
Drosophila        DEVTTQGLDDLAARCAQYKKDGCDFAKWRCVLKIGKNTPSYQSILENA-NVLARYASICQ
Mus               GETTTQGLDGLSERCAQYKKDGADFAKWRCVLKIGEHTPSALAIMENA-NVLARYASICQ
Homo              GETTTQGLDGLSERCAQYKKDGADFAKWRCVLKIGEHTPSALAIMENA-NVLARYASICQ

Arabidopsis       ENGLVPIVEPEVLTGGSHDIKKCAAVTETVLAAVFKALNYHHVLLEGTLLKPNMVTPGSD
Schistosoma       QNGLVPIVEPEVLPDGDHDLLTAQRVTEQVLAFVYKALADHHVYLEGTLLKPNMVTAGQA
Caenorhabditis    QNGLVPIVEPEILPDGEHCLARGQKITETVLSYVYHALNEHHVFLEGTLLKPNMVTSGQS
Drosophila        SQRIVPIVEPEVLPDGDHDLDRAQKVTETVLAAVYKALSDHHVYLEGTLLKPNMVTAGQS
Mus               QNGIVPIVEPEILPDGDHDLKRCQYVTEKVLAAVYKALSDHHVYLEGTLLKPNMVTPGHA
Homo              QNGIVPIVEPEILPDGDHDLKRCQYVTEKVLAAVYKALSDHHIYLEGTLLKPNMVTPGHA

Arabidopsis       S--PKVAPELIAEYTVTALRRTVPPAIPGIVFLSGIQREEQATLNLNAMNKLDVLKPWTL
Schistosoma       CK-KAYTPQENALATVRALQRTVPPAVPGITFLSGGQSELDATKNLNEINKIPGPKPWAL
Caenorhabditis    FTGEKPSNADIGLATVTALQRGVPSAVPGVVFLSGGQSEEDATLNLNAINQVSGKKPWAL
Drosophila        A--KKNTPEEIALATVQALRRTVPAAVTGVTFLSGGQSEEEATVNLSAINNVPLIRPWAL
Mus               CT-QKFSNEEIAMATVTALRRTVPPAVTGVTFLSGGQSEEEASINLNAINKCPLLKPWAL
Homo              CT-QKFSHEEIAMATVTALRRTVPPAVTGITFLSGGQSEEEASINLNAINKCPLLKPWAL

Arabidopsis       TFSFGGALQQSAIKAWAGKPENVAKAQAKFLTRCKANKDATLGKYTGWASGDSAAFENLV
Schistosoma       TFSFGRALQASVLATWKGKKENVHAAQEELLKLAKANGAAAVGKFEGN-MGTTLGDKSLF
Caenorhabditis    TFSYGRALQASCLAKWAGKDENIAAAQEVLLHRAQVNSLASVGKYTGDASADAAASQSLF
Drosophila        TFSYGRALQASVLRAWAGKKENIAAGQNELLKRAKANGEAACGNYTAGSVKGFAGKDTLH
Mus               TFSYGRALQASALKAWGGKKENLKAAQEEYIKRALANSLACQGKYTPSGQSGAAASESLF
Homo              TFSYGRALQASALKAWGGKKENLKAAQEEYVKRALANSLACQGKYTPSGQAGAAASESLF

Arabidopsis       VIGYRY
Schistosoma       VANHAY
Caenorhabditis    VANHSY
Drosophila        VDDHRY
Mus               ISNHAY
Homo              VSNHAY


[Calreticulin]

Arabidopsis       ------------NSARASAAVIFEERF--DDGWENRWVKSEWKKDDNTAGEWKHTAGNWS
Schistosoma       -MLSILLTL-LLSKYALGHEVWFSETF-PNESIEN-WVQSTYNAEK--QGEFKVEAGKSP
Caenorhabditis    -MKSLCL---LAIVAVVSAEVYFKEEF-NDASWEKRWVQSKHKDD---FGAFKLSAGKFF
Drosophila        MMWCKTVIVLLATVGFISAEVYLKENF-DNENWEDTWIYSKHPGKE--FGKFVLTPGTFY
Mus               MLLSVPLLLGLLGLAAADPAIYFKEQFLDGDAWTNRWVESKHKSD---FGKFVLSSGKFY
Homo              MLLSVPLLLGLLGLAVAEPAVYFKEQFLDGDGWTSRWIESKHKSD---FGKFVLSSGKFY

Arabidopsis       GDA-NDKGIQTSEDYRFYAISAEF-PEFSNKDKTLVFQFSVKHEQKLDCGGGYMKLLSGD
Schistosoma       VDPIEDLGLKTTQDARFYGIARKISEPFSNRGKTILLQFTVKFDKTVSCGGAYIKLLGSD
Caenorhabditis    DVESRDQGIQTSQDAKFYSRAAKFDKDFSNKGKTLVIQYTVKHEQGIDCGGGYVKVMRAD
Drosophila        NDAEADKGIQTSQDARFYAASRKF-DGFSNEDKPLVVQFSVKHEQNIDCGGGYVKLFDCS
Mus               GDLEKDKGLQTSQDARFYALSAKF-EPFSNKGQTLVVQFTVKHEQNIDCGGGYVKLFPSG
Homo              GDEEKDKGLQTSQDARFYALSASF-EPFSNKGQTLVVQFTVKHEQNIDCGGGYVKLFPNS

Arabidopsis       VDQKKFGGDTPYSIMFGPDICGYSTKKVHAILTYNGANHLIKKDVPCETDQLTHVYTFIL
Schistosoma       IDPKKFHGESPYKIMFGPDICGMATKKVHVIFNYKGKNHLIKKEIPCKDDLKTHLYTLIV
Caenorhabditis    ADLGDFHGETPYNVMFGPDICGP-TRRVHVILNYKGENKLIKKEITCKSDELTHLYTLIL
Drosophila        LDQTDMHGESPYEIMFGPDICGPGTKKVHVIFSYKGKNHLISKDIRCKDDVYTHFYTLIV
Mus               LDQKDMHGDSEYNIMFGPDICGPGTKKVHVIFNYKGKNVLINKDIRCKDDEFTHLYTLIV
Homo              LDQTDMHGDSEYNIMFGPDICGPGTKKVHVIFNYKGKNVLINKDIRCKDDEFTHLYTLIV

Arabidopsis       RPDATYSILIDNVEKQTGSLYSDWDLLPPKKIKDPSAKKPEDWDEQEYISDPEDKKTDGY
Schistosoma       NPNNKYEVLVDN------A--------------DPNDKKPDDWVDEQFIDDPDDKKPDNW
Caenorhabditis    NSDNTYEVKIDGESAQTGSLEEDWDLLPAKKIKDPDAKKPEDWDEREYIDDAEDAKPEDW
Drosophila        RPDNTYEVLIDNEKVESGNLEDDWDFLAPKKIKDPTATKPEDWDDRATIPDPDDKKPEDW
Mus               RPDNTYEVKIDNSQVESGSLEDDWDFLPPKKIKDPDAAKPEDWDERAKIDDPTDSKPEDW
Homo              RPDNTYEVKIDNSQVESGSLEDDWDFLPPKKIKDPDASKPEDWDERAKIDDPTDSKPEDW

Arabidopsis       DDIPKEIPDTDSKKPEDWDDEEDGEWTAPTIPNPEYMGEWKPKQIKNPNYKGKWEAPLID
Schistosoma       DQ-PKTIPDMDAKKPDDWDDAMDGEWERPQKDNPEYKGEWTPRRIDNPKYKGEWKPVQID
Caenorhabditis    EK-PEHIPDPDAKKPEDWDDEMDGEWEPPMIDNPEYKGEWKPKQIKNPAYKGKWIHPEIE
Drosophila        DK-PEHIPDPDATKPEDWDDEMDGEWEPPMIDNPEFKGEWQPKQLDNPNYKGAWEHPEIA
Mus               DK-PEHIPDPDAKKPEDWDEEMDGEWEPPVIQNPEYKGEWKPRQIDNPDYKGTWIHPEID
Homo              DK-PEHIPDPDAKKPEDWDEEMDGEWEPPVIQNPEYKGEWKPRQIDNPDYKGTWIHPEID

Arabidopsis       NPDFKDDPELYVFPKLKYVGLELWQVKSGSLFDNVLICDDPDYAKKLADETWGKLKDAEK
Schistosoma       NPEYKHDPELYVLNDIGYVGFDLWQVDSGSIFDNILITDSPDFAKEEGERLWRKRYDAEV
Caenorhabditis    NPEYTPDDELYSYESWGAIGFDLWQVKSGTIFDNIIITDSVEEAEAHAAETFDKLKTVEK
Drosophila        NPEYVPDDKLYLRKEICTLGFDLWQVKSGTIFDNVLITDDVELAAKAAAEV-KNTQAGEK
Mus               NPEYSPDANIYAYDSFAVLGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKAAEK
Homo              NPEYSPDPSIYAYDNFGVLGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKAAEK

Arabidopsis       AAFDEAEKKNEEEESKDAPAESDAEDEPEDDEGGDDSDSESKAEETKSEDSEETSEKDAT
Schistosoma       A----KEQSSAKDDKEEAEETKE-RKELP--------D------DAKASDEPSG---D--
Caenorhabditis    EKKEKADEETRKAEEEARKKAEE-EKEAK--KD----D------DEEEKEEEEG------
Drosophila        KMKEAQDEVQRKKDEEEAKKASD-KDDED--ED----DDDEEKDDESKQDKDQS---E--
Mus               QMKDKQDEEQRLKEEEEDKKRKE-EEEAEDKEDDDDRDEDEDEEDEKEEDEEES---PGQ
Homo              QMKDKQDEEQRLKEEEEDKKRKE-EEEAEDKEDDEDKDEDEEDEEDKEEDEEED--VPGQ

Arabidopsis       AHDEL
Schistosoma       -HDEL
Caenorhabditis    -HDEL
Drosophila        -HDEL
Mus               AKDEL
Homo              AKDEL


[Elongation factor 1-alpha]

Arabidopsis       MGKEKFHINIVVIGHVDSGKSTTTGHLIYKLGGIDKRVIERFEKEAAEMNKRSFKYAWVL
Schistosoma       MPSDKEHINIVVYGHVDSGKSTTTGHLIFKCGGIDKRAIEKYEKESGEMGKGSFKYAWVL
Caenorhabditis    MGKEKVHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVL
Drosophila        MGKEKIHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVL
Mus               MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVL
Homo              MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVL

Arabidopsis       DKLKAERDRGITIDIALWKFETTKYYCTVIDAPGHRDFIKNMITGTSQADCAVLIIDSTT
Schistosoma       VKLKAERERGITIDIVLWKFDTQTYKVTVIDAPGHRDFTTNMITGTSQADCAVLIVAAGV
Caenorhabditis    DKLKAERERGITIDIALWKFETAKYYITIIDAPGHRDFIKNMITGTSQADCAVLVVACGT
Drosophila        DKLKAERERGITIDIALWKFETAKYYVTIIDAPGHRDFIKNMITGTSQADCAVQIDAAGT
Mus               DKLKAERERGITIDISLWKFETTKYYITIIDAPGHRDFIKNMITGTSQADCAVLIVAAGV
Homo              DKLKAERERGITIDISLWKFETSKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGV

Arabidopsis       GGFEAGISKDGQTREHALLAFTLGVKQMICCCNKMDATTPKYSKARYDEIIKEVSSYLKK
Schistosoma       GEFEAGISKNGQTREHALLAYTLGVKQLIIAINKMDCTEPPFSEDRYKEIVKEVSGYIKK
Caenorhabditis    GEFEAGISKNGQTREHALLAQTLGVKQLIVACNKMDSTEPPFSEARFTEITNEVSGFIKK
Drosophila        GEFEAGISKNDQTREHALLAFTLGVKQLIVGVNKMDSSEPPYSEARYEEIKKEVSSYIKK
Mus               GEFEAGISKNGQTREHALLAYTLGVKQLIVGVNKMDSTEPAYSEKRYDEIVKEVSAYIKK
Homo              GEFEAGISKNGQTREHALLAYTLGVKQLIVGVNKMDSTEPPYSQKRYEEIVKEVSTYIKK

Arabidopsis       VGYNPDKIPFVPISGFEGDNMIERSTNLDWYK----------------GPTLLEALDQIN
Schistosoma       VGYNPATVPFVPISGWHGDNMIEKSSFMPWFKGWEITRTKDGKTVTDTGFTLLEALDKME
Caenorhabditis    IGYNPKAVPFVPISGFNGDNMLEVSSNMPWFKGWAVER-KEGNAS---GKTLLEALDSII
Drosophila        VGYNPAAVAFVPISGWHGDNMLEPSTNMPWFKGWEVGR-KEGNAD---GKTLVDALDAIL
Mus               IGYNPATVPFVPISGWHGDNMLEPSPNMPWFKGWKVER-KEGNAS---GVSLLEALDTIL
Homo              IGYNPDTVAFVPISGWNGDNMLEPSANMPWFKGWKVTR-KDGNAS---GTTLLEALDCIL

Arabidopsis       EPKRPSDKPLRLPLQDVYKIGGIGTVPVGRVETGMIKPGMVVTFAPTGLTTEVKSVEMHH
Schistosoma       PPARMTDKPLRIPLQDVYKIGGMGTVPVGRVETGIIKPGMVVTFGPQGWSAEVKSVEMHH
Caenorhabditis    PPQRPTDRPLRLPLQDVYKIGGIGTVPVGRVETGIIKPGMVVTFAPQNVTTEVKSVEMHH
Drosophila        PPARPTDKALRLPLQDVYKIGGIGTVPVGRVETGVLKPGTVVVFAPANITTEVKSVEMHH
Mus               PPTRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGILRPGMVVTFAPVNITTEVKSVEMHH
Homo              PPTRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVLKPGMVVTFAPVNVTTEVKSVEMHH

Arabidopsis       ESLLEALPGDNVGFNVKNVAVKDLKRGYVASNSKDDPAKGAANFTSQVIIMNHPGQIGNG
Schistosoma       EALTEGLPGSNVGFNVKNVAVSEIHRGNVAGDSKNDPPKEAESFMAQVIVLNHPGEIKNG
Caenorhabditis    ESLPEAVPGDNVGFNVKNVSVKDIRRGSVCSDSKQDPAKEARTFHAQVIIMNHPGQISNG
Drosophila        EALQEAVPGDNVGFNVKNVSVKELRRGYVAGDSKANPPKGAADFTAQVIVLNHPGQIANG
Mus               EALSEALPGDNVGFNVKNVSVKDIRRGNVCGDSKADPPQEAAQFTSQVIILNHPGQISAG
Homo              EALSEALPGDNVGFNVKNVSVKDVRRGNVAGDSKNDPPMEAAGFTAQVIILNHPGQISAG

Arabidopsis       YAPVLDCHTSHIAVKFSEILTKIDRRSGKEIEKEPKFLKNGDAGMVKMTPTKPMVVETFS
Schistosoma       YSPVLDCHTAHIASKFSEITEKLDRRSGKKSEDNPKCIKNGDAANILLVPNKPLCLETFQ
Caenorhabditis    YTPVLDCHTAHIACKFNELKEKVDRRTGKKVEDFPKFLKSGDAGIVELIPTKPLCVESFT
Drosophila        YTPVLDCHTAHIACKFAEILEKVDRRSGKTTEENPKFIKSGDAAIVNLVPSKPLCVEAFQ
Mus               YSPVIDCHTAHIACKFAELKEKIDRRSGKKLEDNPKSLKSGDAAIVEMVPGKPMCVESFS
Homo              YAPVLDCHTAHIACKFAELKEKIDRRSGKKLEDGPKFLKSGDAAIVDMVPGKPMCVESFS

Arabidopsis       EYPPLGRFAVRDMRQTVAVGVIKSVDKKDPTGAKVTKAAVK-KGAK-
Schistosoma       QYPPLGRFAVRDMNQTVAVGVVKSVTKKE-SAAKVTKSAAKVAKKK-
Caenorhabditis    DYAPLGRFAVRDMRQTVAVGVIKSVEKSDGSSGKVTKSAQKAAPKKK
Drosophila        EFPPLGRFAVRDMRQTVAVGVIKAVNFKDASGGKVTKAAEKATKGKK
Mus               QYPPLGRFAVRDMRQTVAVGVIKNVEKKSGGAGKVTKSAQKAQKAGK
Homo              DYPPLGRFAVRDMRQTVAVGVIKAVDKKAAGAGKVTKSAQKAQKAK-


[Enolase]

Arabidopsis       MATITVVKARQIFDSRGNPTVEVDIHTSNGIKVTAAVPSGASTGIYEALELRDGGSD-YL
Schistosoma       M-SILTIHARQIFDSRGNPTVEVDLKTSKGL-FRAAVPSGASTGVHEALELRDTNSKAYM
Caenorhabditis    M-PITKIHARQIYDSRGNPTVEVDLFTEKGV-FRAAVPSGASTGVHEALELRDGDKAVHL
Drosophila        M-TIKAIKARQIYDSRGNPTVEVDLTTELGL-FRAAVPSGASTGVHEALELRDNDKANYH
Mus               M-SILRIHAREIFDSRGNPTVEVDLYTAKGL-FRAAVPSGASTGIYEALELRDNDKTRFM
Homo              M-SILKIHAREIFDSRGNPTVEVDLFTSKGL-FRAAVPSGASTGIYEALELRDNDKTRYM

Arabidopsis       GKGVSKAVGNVNNIIGPALIGK--DPTQQTAIDNFMVHELDGTQNEWGWCKQKLGANAIL
Schistosoma       KKGVLTAVSNVNKIIAPALINKNIPVTNQAAIDKYMI-DLDGTEN-----KEKLGANAIL
Caenorhabditis    GKGVLKAVSNINEKIAPALIAKGFDVTAQKDIDDFMM-ALDGSEN-----KGNLGANAIL
Drosophila        GKSVLKAVGHVNDTLGPELIKANLDVVDQASIDNFMI-KLDGTEN-----KSKFGANAIL
Mus               GKGVSQAVEHINKTIAPALVSKKVNVVEQEKIDKLMI-EMDGTEN-----KSKFGANAIL
Homo              GKGVSKAVEHINKTIAPALVSKKLNVTEQEKIDKLMI-EMDGTEN-----KSKFGANAIL

Arabidopsis       AVSLAVCKAGAVVSGIPLYKHIANLAGNPKIVLPVPAFNVINGGSHAGNKLAMQEFMILP
Schistosoma       GVSLAVCKAGAAEAGLPLYRYIARLAGHEDVIMPVPAFNVINGGSHAGNKLAMQEFMILP
Caenorhabditis    GVSLAVAKAGAVHKGLPLYKYIAELAGTGKVVLPVPAFNVINGGSHAGNKLAMQEFMILP
Drosophila        GVSLAVAKAGAAKKGVPLYKHIADLAGNKEIILPVPAFNVINGGSHAGNKLAMQEFMILP
Mus               GVSLAVCKAGAVEKGVPLYRHIADLAGNPEVILPVPAFNVINGGSHAGNKLAMQEFMILP
Homo              GVSLAVCKAGAVEKGVPLYRHIADLAGNSEVILPVPAFNVINGGSHAGNKLAMQEFMILP

Arabidopsis       VGAASFKEAMKMGVEVYHHLKSVIKKKYGQDATNVGDEGGFAPNIQENKEGLELLKTAIE
Schistosoma       TGASSFTEAMQIGTEVYHNLKAVIKREYGLDACNVGDEGGFAPNIQDNMKGLQLLEEAIK
Caenorhabditis    VGASSFAEAMRMGSEVYHHLKAEIKKRYGLDATAVGDEGGFAPNIQDNKEGLDLLNTAID
Drosophila        TGATSFTEAMKMGSEVYHHLKNVIKAKFGLDATAVGDEGGFAPNIQSNKEALNLISDAIA
Mus               VGASSFREAMRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEALELLKTAIA
Homo              VGAANFREAMRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEGLELLKTAIG

Arabidopsis       KAGYTGKVVIGMDVAASEFYSEDKTYDLNFKEENNNGSQKISGDALKDLYKSFVAEYPIV
Schistosoma       IAGYTGKVEIGMDCAASEFHKNGK-YDLDFKNPHSAESTWLSPDAMANMYKQMISKFPIV
Caenorhabditis    KAGYTGKISIGMDVAASEFFKDGK-YDLDFKNPASDSSKWLSGEQLTELYQSFIKEYPVV
Drosophila        KAGYTGKIEIGMDVAASEFYKDGQ-YDLDFKNEKSDKSQWLPADKLANLYKEFIKDFPIV
Mus               KAGYTDQVVIGMDVAASEFYRSGK-YDLDFKSP-DDPSRYITPDQLADLYKSFVQNYPVV
Homo              KAGYTDKVVIGMDVAASEFFRSGK-YDLDFKSP-DDPSRYISPDQLADLYKSFIKDYPVV

Arabidopsis       SIEDPFDQDDWEHYAKMTTECGTEVQIVGDDLLVTNPKRVAKAIAEKSCNALLLKVNQIG
Schistosoma       SIEDPFDQDDWETWPKLTS--STNIQIVGDDLTVTNPKRIKQAIASKACNCLLLKVNQIG
Caenorhabditis    SIEDAFDQDDWDNWGKFHG--ATSIQLVGDDLTVTNPKRIQTAIDKKSCNCLLLKVNQIG
Drosophila        SIEDPFDQDHWEAWSNLTG--CTDIQIVGDDLTVTNPKRIATAVEKKACNCLLLKVNQIG
Mus               SIEDPFDQDDWGAWQKFTA--SAGIQVVGDDLTVTNPKRIAKAASEKSCNCLLLKVNQIG
Homo              SIEDPFDQDDWGAWQKFTA--SAGIQVVGDDLTVTNPKRIAKAVNEKSCNCLLLKVNQIG

Arabidopsis       SVTESIEAVKMSKKAGWGVMTSHRSGETEDTFIADLAVGLSTGQIKTGAPCRSERLAKYN
Schistosoma       SLTESIEACKLAQDSGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSDRLAKYN
Caenorhabditis    SVTESIEAAKLSRANGWGVMVSHRSGETEDTFIADLVVGLATGQIKTGAPCRSERLAKYN
Drosophila        TVTESIAAHLLAKKNGWGTMVSHRSGETEDSFIGDLVVGLSTGQIKTGAPCRSERLAKYN
Mus               SVTESLQACKPAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYN
Homo              SVTESLQACKLAQANGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYN

Arabidopsis       QLLRIEEELGSEAIYAGVNFRKPVEPY
Schistosoma       QLLRIEEELGTAAKYAGKNFRHPKV--
Caenorhabditis    QLLRIEEELGADAVYAGHNFRNPQV--
Drosophila        QILRIEEEIGAGVKFAGKSFGKPQ---
Mus               QILRIEEELGSKAKFAGRSFRNPLAK-
Homo              QLLRIEEELGSKAKFAGRNFRNPLAK-


[Glyceraldehyde-3-phosphate dehydrogenase]

Arabidopsis       MASVTFSVPKGFTEFSGLRSSSASLPFGKKLSSDEFVSIVSFQTSAMGSSGGYRKGVTEA
Schistosoma       ------------------------------------MS----------------------
Caenorhabditis    ------------------------------------MS----------------------
Drosophila        ------------------------------------M-----------------------
Mus               ------------------------------------M-----------------------
Homo              ------------------------------------MG----------------------

Arabidopsis       KLKVAINGFGRIGRNFLRCWHGRKDSPLDIIAINDTG-GVKQASHLLKYDSTLGIFDADV
Schistosoma       KAKVGINGFGRIGRLVLRA--AFLKNTVDIVAVNDPFIDLEYMVYMIKYDSTHGKFQGDV
Caenorhabditis    KANVGINGFGRIGRLVLRA--AVEKDTVQVVAVNDPFITIDYMVYLFKYDSTHGQFKGTV
Drosophila        -SKIGINGFGRIGRLVLRA--AIDKG-ASVVAVNDPFIDVNYMVYLFKFDSTHGRFKGTV
Mus               -VKVGVNGFGRIGRLVTRA--AICSGKVEIVAINDPFIDLNYMVYMFQYDSTHGKFNGTV
Homo              KVKVGVNGFGRIGRLVTRA--AFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTV

Arabidopsis       KPSGETAISV--DGK---IIQVVSNRNPSLLPWKELGIDIVIEGTGVFVDREGAGKHMEA
Schistosoma       SVENGK-LNV--NGR---LISVYCERDPLNIPWNKDGAEYVVESTGVFTTIDKAQAHIKN
Caenorhabditis    TYDGDF-LIVQKDGKSSHKIKVFNSKDPAAIAWGSVKADFVVESTGVFTTKEKASAHLQG
Drosophila        AAEGGF-LVV--NGQ---KITVFSERDPANINWASAGAEYVVESTGVFTTIDKASTHLKG
Mus               KAENGK-LVI--NGK---PITIFQERDPTNIKWGEAGAEYVVESTGVFTTMEKAGAHLKG
Homo              KAENGK-LVI--NGN---PITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQG

Arabidopsis       G-AKKVIITAPGKGDIPTYVVGVNADAYSHDEP-IISNASCTTNCLAPFVKVLDQKFGII
Schistosoma       DRAKKVIISAP-SADAPMFVVGVNEKTYDKSMS-VVSNASCTTNCLAPLAKVINDNFEIV
Caenorhabditis    G-AKKVIISAP-SADAPMYVVGVNHEKYDASNDHVVSNASCTTNCLAPLAKVINDNFGII
Drosophila        G-AKKVIISAP-SADAPMFVCGVNLDAYSPDMK-VVSNASCTTNCLAPLAKVINDNFEIV
Mus               G-AKRVIISAP-SADAPMFVMGVNHEKYDNSLK-IVSNASCTTNCLAPLAKVIHDNFGIV
Homo              G-AKRVIISAP-SADAPMFVMGVNHEKYDNSLK-IISNASCTTNCLAPLAKVIHDNFGIV

Arabidopsis       KGTMTTTHSYTGDQRLLDASHRDL-RRARAAALNIVPTSTGAAKAVALVLPNLKGKLNGI
Schistosoma       EGLMTTVHSFTATQKTVDGPSSKLWRDGRGAFQNIIPASTGAAKAVGKVIPALNGKLTGM
Caenorhabditis    EGLMTTVHAVTATQKTVDGPSGKLWRDGRGAGQNIIPASTGAAKAVGKVIPELNGKLTGM
Drosophila        EGLMTTVHATTATQKTVDGPSGKLWRDGRGAAQNIIPAATGAAKAVGKVIPALNGKLTGM
Mus               EGLMTTVHAITATQKTVDGPSGKLWRDGRGAAQNIIPASTGAAKAVGKVIPELNGKLTGM
Homo              EGLMTTVHAITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELDGKLTGM

Arabidopsis       ALRVPTPNVSVVDLVVQVSKKTFAEEVNAAFRDSAEKELKGILDVCDEPLVSVDFRCSDF
Schistosoma       AFRVPTANVSVVDLTCRLGKGATYDQIKAVIKAAANGPLKGILEYTEDEVVSSDFIGCTS
Caenorhabditis    AFRVPTPDVSVVDLTVRLEKPASMDDIKKVVKAAADGPMKGILAYTEDQVVSTDFVSDPH
Drosophila        AFRVPTPNVSVVDLTVRLGKGATYDEIKAKVEEASKGPLKGILGYTDEEVVSTDFLSDTH
Mus               AFRVPTPNVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEDQVVSCDFNSNSH
Homo              AFRVPTANVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTH

Arabidopsis       STTIDSSLTMVMGDDMVKVIAWYDNEWGYSQRVVDLADIVANNWK-
Schistosoma       SSIFDAKAGISLNNNFVKLVSWYDNEFGYSCRVVDLITHMHRVDHS
Caenorhabditis    SSIFDAGACISLNPNFVKLVSWYDNEYGYSNRVVDLIGYIATRG--
Drosophila        SSVFDAKAGISLNDKFVKLISWYDNEFGYSNRVIDLIKYMQSKD--
Mus               SSTFDAGAGIALNDNFVKLISWYDNEYGYSNRVVDLMAYMASKE--
Homo              SSTFDAGAGIALNDHFVKLISWYDNEFGYSNRVVDLMAHMASKE--


[3-hydroxy-3-methylglutaryl coenzyme A reductase
HMG-CoA reductase]

Arabidopsis       ----------MDLRRRP--------PKPPVTNNNNSN---------GSF-----------
Schistosoma       MLKILNTVL-LFFDCFSTGTFFVLLIYLFTRLRTHLLHFSS-----SNCHLD--------
Caenorhabditis    ----------MILKT----------SASIVKSRGGIL---------SAF-----------
Drosophila        MIGPLFRAT-QFCASHPWEVIVALLTITACMLNGGQEQYPGCEQRIGHSTASAAAAGSGS
Mus               ------------------------------------------------------------
Homo              MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMF--TG-----NNK-----------

Arabidopsis       R---------------SY-----------QPRT-----SDDDHR-RRATTIAPPPKAS--
Schistosoma       VI--------------IYQSRAVIIFLVVFVYFIGVLTCKINDK-ILVHTMLRNKRQLNT
Caenorhabditis    C---------------FF-------------YF-----CRYRFY-INLMNI---------
Drosophila        GAGSGASGTIPPSSMGGSATSSRHRPCHGWSQSCDGLEAEYNAADVILMTIVRCTAVLYC
Mus               ------------------------------------------------------------
Homo              I---------------CG-----------WNYECPKFEEDVLSSDIIILTITRCIAILYI

Arabidopsis       DA------------LPLPLYL----TNAVFFTLF------------FSVAYY--------
Schistosoma       LFYTLILFTFALCSLSSVLFVPYTSFAIFLLSTS-VFLLFSDLSVFFIVLEYYLLEIELV
Caenorhabditis    YF------------LNNPISV----VRSTLASGN------------QNIMVA--------
Drosophila        YYQFCSLHRLGSKYVLGIAGL-FTVFSSFIFTTAIIKFLGSDISELKDALFFLLLVIDLS
Mus               ------------------------------------------------------------
Homo              YFQFQNLRQLGSKYILGIAGL-FTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLS

Arabidopsis       ----LLHRWRDK--------------IRYNTP-LHVVTITELGAI--------IAL----
Schistosoma       NYEHAKRHCLLSHLFSNQLFVDHMLGMFLKTSLFSISTTSKYAYLESIFKCTLMEQIIYI
Caenorhabditis    ----DKRKLLD----------------FLQSCDISDEASRKIENF--------ICE----
Drosophila        NSGRLRSGAMGSN--QAEVTQNIARGLELLGPAISLDTIVVVLLV-GVGTLSGVQR-LEV
Mus               ------------------------------------------------------------
Homo              RASTLAKFALSSNS-QDEVRENIARGMAILGPTFTLDALVECLVI-GVGTMSGVRQ-LEI

Arabidopsis       -------------IASFIY-----------LL--------GFFGIDFVQSF---------
Schistosoma       MIVFVFLPSFMRIFASYAKRMYGEQKKCLVSNKGVSSSTRKRRHSYSSGHSYVEYRRMSV
Caenorhabditis    -------------NYDQKE-----------KP--------KRKPLFSVGED---------
Drosophila        LCMF----AVLSVLVNYVV-FMTFYPACLSLIFDLSRSGVDMSVVREKAKGSLPLKSLT-
Mus               ------------------------------------------------------------
Homo              MCCF----GCMSVLANYFV-FMTFFPACVSLVLELSRESREGRPIWQLSHF---ARVLE-

Arabidopsis       ---------------------I----------------SR--------ASGDAWD----L
Schistosoma       HNLIGYVVNPNCHYKCWSTTFVIFVSLIILHLNNRYS-ERISSFKHNSSENEVFPVL--Y
Caenorhabditis    --------------------------------------DD--------SEEYVSP----I
Drosophila        ----EEEQKANPVLQRVKL--IMTTGLMAVHIYSREV-SPAATTMVDKTLTPTLSLN--V
Mus               ------------------------------------------------------------
Homo              ----EEENKPNPVTQRVKM--IMSLGLVLVHAHSRWIADPSPQNSTADTSKVSLGLDENV

Arabidopsis       ADT-IDDDD---------HRLVTCS--------------------------------PPT
Schistosoma       HITAYEVTS-IFHFIYNIFHVINANLVVYLFLGLFL-FKRIRLNK--PINSQ-LRN-LNI
Caenorhabditis    KET-CETGT---------QCKRDVE--------------------------------YPE
Drosophila        SNNRTESGE-IADIIIK-WLTMSADHIVISIVLIALVVKFICFDNRDPLPDQ-LR--QSG
Mus               ------------------------------------------------------------
Homo              SKR-IEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQTETESTLSLKNPITS

Arabidopsis       PIVSVAKLP-NP------------------------------------------EPIV--
Schistosoma       PKIKETLISDQV-KQSPVLP------KFSKKLNDIPLQSRKR-IYCLHKDDDYIDRND--
Caenorhabditis    IESGNRSLD-EI------------------------------------------SREW--
Drosophila        PVAIEAKAS-QT---TPIDE------EHVEQEKDTENSAAVRTLLFTIEDQSSANAST--
Mus               ------------------------------------------------------------
Homo              PVVTQKKVPDNCCRREPMLVRNNQKCDSVEEETGINRERKVEVIKPLVAETDTPNRATFV

Arabidopsis       ----------------T-------------ESLP-------------EEDEEIVKSVIDG
Schistosoma       --SSSVSTFSNTCKN-S-----NERPSNVLDLDMLTEKIKQGLGHE-LSDTEILQLLSHG
Caenorhabditis    ----------------K-------------ECKD-------------VTPGEAVRLLRRG
Drosophila        --QTDLLPLRHRLVG-P-----IKPPRPVQECLDILNSTEEGSGPAALSDEEIVSIVHAG
Mus               ------------------------------------------------------------
Homo              VGNSSLLDTSSVLVTQEPEIELPREPRPNEECLQILGNAEKGAKF--LSDAEIIQLVNAK

Arabidopsis       --VIPSYSLESRLGDCKRAASIRREALQRVTGR---SIEGLPLDGFDYESILGQCCEMPV
Schistosoma       --RLKTRELESVVRNPFRAVELRRLDLSTFLNNPH-IIERIPYKDYDYRLVYGQCCEEVI
Caenorhabditis    --QAKSRELESRF-PAEQAIPIRRTFINK---K----FENLPYLGYDYTLATECCCENVI
Drosophila        GTHCPLHKIESVLDDPERGVRIRRQIIGSRAKMPVGRLDVLPYEHFDYRKVLNACCENVL
Mus               ------------------------------------------------------------
Homo              --HIPAYKLETLMETHERGVSIRRQLLSKKLSEPS-SLQYLPYRDYNYSLVMGACCENVI

Arabidopsis       GYIQIPVGIAGPLLLDG-YEYSVPMATTEGCLVASTNRGCKAMFISGGATSTVLKDGMTR
Schistosoma       GYMPIPVGKIGPLLLDG-RSHYIPLATTEGCLVASTNRGCRAIFLAGGIKSVVYRDQMTR
Caenorhabditis    GYTPVPVGVAGPLTLNGTSEIYVPMATTEGALIASTNRGMNVIRAAGGVETSIFNSGMTR
Drosophila        GYVPIPVGYAGPLLLDG-ETYYVPMATTEGALVASTNRGCKALSVRG-VRSVVEDVGMTR
Mus               -------------------------------------E--KAL----------LK-----
Homo              GYMPIPVGVAGPLCLDE-KEFQVPMATTEGCLVASTNRGCRAIGLGGGASSRVLADGMTR

Arabidopsis       APVVRFASARRASELKFFLENPENFDTLAVVFNRSSRFARLQSVKCTIAGKNAYVRFCCS
Schistosoma       APVVWFPSIIDSVKCIAWIDSEEGFQTLKSAFDKTSAHVNLLSVFACPAGRYIHIRFAAR
Caenorhabditis    APVVKFPTARDAVSMKRWLEHPENQDRARQEFQSCSRFAKLKSIDITIDGNLAYLRFDAH
Drosophila        APCVRFPSVARAAEAKSWIENDENYRVVKTEFDSTSRFGRLKDCHIAMDGPQLYIRFVAI
Mus               ------------------------------------------------------------
Homo              GPVVRLPRACDSAEVKAWLETSEGFAVIKEAFDSTSRFARLQKLHTSIAGRNLYIRFQSR

Arabidopsis       TGDAMGMNMVSKGVQNVLEYLTDDFPDMDVIGISGNFCSDKKPAAVNWIEGRGKSVVCEA
Schistosoma       TGDAMGMNMVSKATDSALHCLKKYFSNMQVISLSGNMCTDKKPATINTILGRGKSVIAEA
Caenorhabditis    TGDAMGMNMISKSCDSTMRFLMENFPEMTVLALSGNLCVDKKAAAKNWTEGRGRSVVAEC
Drosophila        TGDRMGMNMVSKALRWPFAEFTLHFPDMQIISLSGNFCCDKKPAAINWIKGRGKRVVTEC
Mus               --------------------LQEFFPDMQILAVSGNYCTDKKPAAINWIEGRGKTVVCEA
Homo              SGDAMGMNMISKGTEKALSKLHEYFPEMQILAVSGNYCTDKKPAAINWIEGRGKSVVCEA

Arabidopsis       VIRGEIVNKVLKTSVAALVELNMLKNLAGSAVAGSLG--GFNAHASNIVSAVFIATGQDP
Schistosoma       HLSADVLAQVLHTNAQRLARLTHSKNWIGSAMAGCPGMMGCNAHAANIIAGMFAATGQDL
Caenorhabditis    LIPREVVTKTLRTTPEQLAYLTTTKLHIGSSRAGAVG--GSNAHAANIVAAIFIATGQDA
Drosophila        TISAATLRSVLKTDAKTLVECNKLKNMGGSAMAGSIG--GNNAHAANMVTAVFLATGQDP
Mus               VIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIG--GYNAHAANIVTAIYIACGQDA
Homo              VIPAKVVREVLKTTTEAMIEVNINKNLVGSAMAGSIG--GYNAHAANIVTAIYIACGQDA

Arabidopsis       AQNVESSQCITMMEAIN-DGKDIHISVTMPSIEVGTVGGGTQLASQSACLNLLGVKGAST
Schistosoma       AQVVDSSSCLTQLEVDL-SDDSLVASVTMPCLEVGTVGGGTRLSGQRACLDLLDL---SV
Caenorhabditis    AQVVSSSMCSTRMEVTA--DKNLYVSCTLPCVEVGTVGGGTILAPQRACLESLGCAGPNK
Drosophila        AQNVTSSNCSTAMECWAENSEDLYMTCTMPSLEVGTVGGGTGLPGQSACLEMLGVRGAHA
Mus               AQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACK
Homo              AQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACK

Arabidopsis       ESPGMNARRLATIVAGAVLAGELSLMSAIAAGQLVRSHMKYNRSS------------RDI
Schistosoma       DRPTEH---LSRIIAGTVLAAELSLMAALDTDDLVKAHMHFNRAKQSTNSHSCSHSTTTD
Caenorhabditis    EQPGQNAERLAEVIAATVLAGELSLMAALTTNELVSSHMKLNRSK------------QQL
Drosophila        TRPGDNAKKLAQIVCATVMAGELSLMAALVNSDLVKSHMRHNRSS------------IAV
Mus               DNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSK------------INL
Homo              DNPGENARQLARIVCGTVMAGELSLMAALAAGHLVKSHMIHNRSK------------INL

Arabidopsis       --------SGATT---------TTTTTT-----------------------------
Schistosoma       NNDNISNIYDNHNVALSSKIPVTDNSDIRESVHSLHVKPFPVKSDLSVNPEISHYTM
Caenorhabditis    YADD-SG-KATHFEKEVEKAGSLLSGKSG------NIKLKRLPQDVVQCSNIL----
Drosophila        --------NSANN---------PLNVTVS------------S------CSTIS----
Mus               --------QDLQG---------TCTKKAA----------------------------
Homo              --------QDLQG---------ACTKKTA----------------------------


[Phosphoglycerate kinase]

Arabidopsis       ----GDLT--SADLKGKKVFVRADLNVPLDDNQTITDDTRIRAAIPTIKYLIENGAK-VI
Schistosoma       MGL-SKLSISDVDLKGKRVLIRVDFNVPMKDGK-VTNTQRIAAAIPTIKYALDKGAKSVV
Caenorhabditis    MSSLNKLAIDQLNLAGKRVLIRVDFNVPLKDGK-ITNNQRIAAAVPTIQHALSNGAKSVV
Drosophila        MAF-NKLSIENLDLAGKRVLMRVDFNVPIKEGK-ITSNQRIVAALDSIKLALSKKAKSVV
Mus               MSLSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQ-ITNNQRIKAAVPSIKFCLDNGANSVV
Homo              MSLSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQ-ITNNQRIKAAVPSIKFCLDNGAKSVV

Arabidopsis       LSTHLGRPKGVT--PKFSLAPLVPRLSELLGIEVTKADDCIGPEVESLVASLPEGGVLLL
Schistosoma       LMSHLGRPDGHKV-DKYSLKPVCPEVSKLLGKEVTFLNDCVGPDVVNACANPAPGSVFLL
Caenorhabditis    LMSHLGRPDGRRQ-DKYTLKPVAEELKALLKKDVLFLDDCVGSEVEAACADPAPGSVILL
Drosophila        LMSHLGRPDGNKN-IKYTLAPVAAELKTLLGQDVIFLSDCVGSEVEAACKDPAPGSVILL
Mus               LMSHLGRPDGVPMPDKYSLEPVAAELKSLLGKDVLFLKDCVGPEVENACANPAAGTVILL
Homo              LMSHLGRPDGVPMPDKYSLEPVAVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILL

Arabidopsis       ENVRFYKEEE-KN----------DP----EFAKKLASLADLYVNDAFGTAHRAHASTEGV
Schistosoma       ENLRFHVEEEGKGVSPTGEKTKATADQIKAFSESLTKLGDVYVNDAFGTAHRAHASMVGC
Caenorhabditis    ENLRYHLEEEGKGVDASGAKVKADSAAVKKFRESLTKLGDIYVNDAFGTAHRAHSSMVGV
Drosophila        ENVRFYVEEEGKGLDASGGKVKADPAKVKEFRASLAKLGDVYVNDAFGTAHRAHSSMMGD
Mus               ENLRFHVEEEGKGKDASGNKVKAEPAKIDAFRASLSKLGDVYVNDAFGTAHRAHSSMVGV
Homo              ENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGV

Arabidopsis       TKFLKPSVAGFLLQKELDYLVGAVSNPKRPFAAIVGGSKVSSKIGVIESLLEKCDILLLG
Schistosoma       Q--LPQKACGFLMNKELTYFAKALENPERPFLAILGGAKVSDKIQLINNMLDKVNELIIG
Caenorhabditis    E--HSQRASGFLLKNELSYFSKALDNPARPFLAILGGAKVADKIQLIKNLLDKVNEMIIG
Drosophila        G--FEQRAAGLLLNKELKYFSQALDKPPNPFLAILGGAKVADKIQLIENLLDKVNEMIIG
Mus               N--LPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIG
Homo              N--LPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIG

Arabidopsis       GGMIFTFYK-AQGLSVGSSLVEEDKLELATELLAKAKAKGVSLLLPTDVVVADKFAPDAN
Schistosoma       GGMAYTFLKQIHNMHIGNSLFDAPGAEIVHKVMETAKAKNVAIHLPVDFVTADKFADDAN
Caenorhabditis    GGMAYTFLKVAQGVKIGNSLYDEEGAKIVNELLEAAKAKGVQIHLPVDFVIADKFAEDAT
Drosophila        GGMAFTFLKVLNNMKIGGSLFDEEGSKIVEKLVEKAKKNNVQLHLPVDFVCGDKFAENAA
Mus               GGMAFTFLKVLNNMEIGTSLYDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAK
Homo              GGMAFTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAK

Arabidopsis       SK-IVPASGIEDGWMGLDIGPDSIKTFNEALDTTQTVIWNGPMGVFEMEKFAAGTEAIAN
Schistosoma       TEIRTIQSGIADGWMGLDIGPKTIEEFSKVISRAKTIVWNGPMGVFEMDKFATGTKAAMD
Caenorhabditis    SKTVTAEEGVPDGHMGLDVGPESSKIFAAAIQRAKTIVWNGPAGVFEFDKFATGTKSLMD
Drosophila        VSEATVEAGIPDGHMGLDVGPKTRELFAAPIARAKLIVWNGPPGVFEFPNFANGTKSIMD
Mus               TGQATVASGIPAGWMGLDCGTESSKKYAEAVGRAKQIVWNGPVGVFEWEAFARGTKSLMD
Homo              TGQATVASGIPAGWMGLDCGPESSKKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMD

Arabidopsis       KLAELSEKGVTTIIGGGDSVAAVEKVGVAGVMSHISTGGGASLELLEGKVLPGVIALDEA
Schistosoma       EVVKATKNGATTIIGGGDTATCCAKWDTEDKVSHVSTGGGASLELLEGKQLPGVVALTDA
Caenorhabditis    EVVKATAAGAITIIGGGDTATAAKKYNTEDKVSHVSTGGGASLELLEGKVLPGVDALSPA
Drosophila        GVVAATKNGTVSIIGGGDTASCCAKWNTEALVSHVSTGGGASLELLEGKTLPGVRALTSA
Mus               EVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVDALSNV
Homo              EVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVDALSNI

Arabidopsis       IPVTV
Schistosoma       H----
Caenorhabditis    Q----
Drosophila        -----
Mus               -----
Homo              -----


[Ribosomal protein L13E]
	
Arabidopsis       M--KHNNVIPNGHFKKHWQNYVKTWFNQPARKTRRRIARQKKAVKIFPRPTSGPLRPVVH
Schistosoma       MV-HGNDVLHHNHFRKKWQFMVKTWFNQPARKERRRQARKAKAQRIAPRPASGPLRPIVN
Caenorhabditis    MAPRGNQMLGNAHFRKHWHKRIKTWFDQPARKLRRRQNRQAKAVEIAPRPVAGLLRSVVR
Drosophila        MG-KGNNMIPNQHYHKWWQRHVKTWFNQPARKVRRHANRVKKAKAVFPRPASGALRPVVR
Mus               MAPSRNGMILKPHFHKDWQQRVDTWFNQPARKIRRRKARLAKARRIAPRPASGPIRPIVR
Homo              MAPSRNGMVLKPHFHKDWQRRVATWFNQPARKIRRRKARQAKARRIAPRPASGPIRPIVR

Arabidopsis       GQTLKYNMKVRTGKGFTLEELKAAGIPKKLAPTIGIAVDHRRKNRSLEGLQTNVQRLKTY
Schistosoma       CPTFRYNMKVRSGRGFSLQEVRAAGLNPKFARTIGIAVDHRRRNVSVEGLQRNVARLKAY
Caenorhabditis    CPQKRYNTKTRLGRGFSLQELKAAGISQAQARTIGIAVDVRRTNKTAEGLKANADRLKEY
Drosophila        CPTIRYHTKLRAGRGFTLEELKGAGIGANFAKTIGIAVDRRRKNKSLESRQRNIQRLKEY
Mus               CPTVRYHTKVRAGRGFSLEELRVAGIHKKVARTIGISVDPRRRNKSTESLQANVQRLKEY
Homo              CPTVRYHTKVRAGRGFSLEELRVAGIHKKVARTIGISVDPRRRNKSTESLQTNVQRLKEY

Arabidopsis       KTKLVIFPRRARKVKAGDSTPEELANATQVQGDYLPIVREKPTM-ELVKLTSEMKSFKAF
Schistosoma       KAKLILFPLNPAKPQAMDAKADEVKKATQLRRPVLPITQRAKRL-KAHKPTSSELRYSAF
Caenorhabditis    KAKLILFPKKASAPKKGDSSAEELKVAAQLRGDVLPLSHTITFD-EPRQVTDAERKVEIF
Drosophila        RSKLILFPINEKKIRAGESSLEECKLATQLKGPVLPIKNEQPAVVEFREVTKDEKKFKAF
Mus               RSKLILFPRKPSAPKKGDSSAEELKLATQLTGPVMPIRNVYKKE-KARVITEEEKNFKAF
Homo              RSKLILFPRKPSAPKKGDSSAEELKLATQLTGPVMPVRNVYKKE-KARVITEEEKNFKAF

Arabidopsis       DKIRLERTNKR-HAGARAKRAAEAEK-EE------KK---
Schistosoma       HAIR-----QQ-----------------------------
Caenorhabditis    RLLRKERADKK-YRGKREKRAREAAE-EN------K----
Drosophila        ATLR-TRTDAR-LVGIRAKRAKEAAESEDAAKGDPKKAKK
Mus               ASLRMARANAPTLWQSEQKRAKEASE-QRCWK---RKN--
Homo              ASLRMARANAR-LFGIRAKRAKEAAE-QDVEK---KK---


[T-complex polypeptide 1 alpha subunit]

Arabidopsis       M-SISAQNPDISGDRQSGQDVRTQNVMACQAVSNIVKTSLGPVGLDKMLVDDIGDVTITN
Schistosoma       M-------LTLGGERTSGESVRKQNVLAACSFANFVKTSLGPVGLDKMLVDDVGDVTITN
Caenorhabditis    MASAGDSILALTGKRTTGQGIRSQNVTAAVAIANIVKSSLGPVGLDKMLVDDVGDVIVTN
Drosophila        M-STLASPLSIAGTRQSRRIVRTQNVMAALSISNIVKSSLGPVGLDKMLVDDIGDVTVTN
Mus               M----EGPLSVFGDRSTGEAVRSQNVMAAASIANIVKSSFGPVGLDKMLVDDIGDVTITN
Homo              M----EGPLSVFGDRSTGETIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITN

Arabidopsis       DGATILRMLEVEHPAAKVLVELAELQDREVGDGTTSVVIVAAELLKRANDLVRNKIHPTS
Schistosoma       DGATILKLLDVEHPAAKILVQLAQLQDEEVGDGTTSVVILAAALLKNADELISRFVHPTT
Caenorhabditis    DGATILKQLEVEHPAGKVLVELAQLQDEEVGDGTTSVVIVAAELLKRADELVKQKVHPTT
Drosophila        DGATILRLLEVEHPAAKVLVELAQLQDEEVGDGTTSVVILAAELLKNADELVKQKIHPTS
Mus               DGATILKLLEVEHPAAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTS
Homo              DGATILKLLEVEHPAAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTS

Arabidopsis       IISGYRLAMRESCKYIEEKLVTKVEKLGKVPLINCAKTSMSSKLISGDSDFFANLVVEAV
Schistosoma       VINGYRLACREACKYIQEHMAYDVNKLGKAGLINVARTAMSSKLINLDADMFSQMAVDAL
Caenorhabditis    IINGYRLACKEAVKYISENISFTSDSIGRQSVVNAAKTSMSSKIIGPDADFFGELVVDAA
Drosophila        IISGYRIACKEACKYISEHLTAPVDELGRDSLINIAKTSMSSKIIGADAEFFSAMVVDAA
Mus               VISGYRLACKEAVRYINENLIINTDELGRDCLINAAKTSMSSKIIGINGDYFANMVVDAV
Homo              VISGYRLACKEAVRYINENLIVNTDELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAV

Arabidopsis       LSVKMTNQRGEIKYPIKGINILKAHGQSARDSYLLNGYALNTGRAAQGMPLRVSPAKIAC
Schistosoma       MAVEVSGGPKGPVYPIKAVNILKAHGRSMSESMLIDGYALNCTAASQQMPRIIKKAKIAF
Caenorhabditis    EAVRVEN-NGKVTYPINAVNVLKAHGKSARESVLVKGYALNCTVASQAMPLRVQNAKIAC
Drosophila        QSVKITDPRGQAVYSIKAVNVLKAHGKSARESVLIPGYALNCTIASQQMPKKIVNAKIAC
Mus               LAVKYTDARGQPRYPVNSVNILKAHGRSQIESMLINGYALNCVVGSQGMPKRIVNAKIAC
Homo              LAIKYTDIRGQPRYPVNSVNILKAHGRSQMESMLISGYALNCVVGSQGMPKRIVNAKIAC

Arabidopsis       LDFNLQKTKMQLGVQVVVNDPRELEKIRQREADMTKERIEKLLKAGANVILTTKGIDDMA
Schistosoma       LDFSLQKVKMKLGVQVVVKDPAQLEAIRQREADITKERIQKILNAGANVILTTGGIDDLC
Caenorhabditis    LDFSLMKAKMHLGISVVVEDPAKLEAIRREEFDITKRRIDKILKAGANVVLTTGGIDDLC
Drosophila        HDFSLQKTKMKMGVQVLINDPDKLEAIRARELDITKERINMILGTGVNVVLVSGGVDDLC
Mus               LDFSLQKTKMKLGVQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDDMY
Homo              LDFSLQKTKMKLGVQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDDMC

Arabidopsis       LKYFVEAGAIAVRRVRKEDMRHVAKATGATLVTTFADMEGEETFDPAHLGSADEVVEERI
Schistosoma       MKYFVEVNAMAVRRCKKVDLKNMAKATGGQLIVSLADMEGDEVFDPTKLGNAEEVSQERI
Caenorhabditis    LKQFVESGAMAVRRCKKSDLKRIAKATGATLTVSLATLEGDEAFDASLLGHADEIVQERI
Drosophila        MKYFVEAGAMAVRRVKKSDLKIIAKATGAAFITSLTNMDGEESFDASMVGEAAEVAQERI
Mus               LKYFVEAGAMAVRRVLKRDLKHVAKASGASILSTLANLEGEETFEVTMLGQAEEVVQERI
Homo              LKYFVEAGAMAVRRVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQERI

Arabidopsis       ADDDVILIKGTKTSSAVSLILRGANDYMLDEMERALHDALCIVKRTLESNTVVAGGGAVE
Schistosoma       CDDELIILRGPKVHPSASIILRGANDFYVDEMERSLHDALLVVKRVLESKRIVPGAGACE
Caenorhabditis    SDDELILIKGPKSRTASSIILRGANDVMLDEMERSVHDSLCVVRRVLESKKLVAGGGAVE
Drosophila        CDDELILIKGTKARAAASIILRGPNDFYCDEMERSVHDALCVVKRVLESKKVVRGGGCVE
Mus               CDDELILIKNTKARTSASIILRGANDFMCDEMERSLHDALCVVKRVLELKSVVPGGGAVE
Homo              CDDELILIKNTKARTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVE

Arabidopsis       SALSVYLEHLATTLGSREQLAIAEFADALLIIPKVLAVNAAKDATELVAKLRAYHHTAQT
Schistosoma       TAVSIYLENYALTLSSREQLAIAEFARAMLSIPKQLAVNAGVDSTELVARLRSCHNSSQS
Caenorhabditis    TSLSLFLETYAQTLSSREQLAVAEFASALLIIPKVLASNAARDSTDLVTFLRAYHSKAQL
Drosophila        AALSIYLENFATSLASREQLAIAEFAKSLLVIPKTLSVNAAKDATDLVAKLRSYHNSSQT
Mus               AALSIYLENYATSMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQV
Homo              AALSIYLENYATSMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQV

Arabidopsis       KADKKHYSSMGLDLVNGTIRNNLEAGVIEPAMSKVKIIQFATEAAITILRIDDMIKL---
Schistosoma       KPDQAHNKWWGLDLNNQYVADCKEIGVFEPLVSKIKSLKFATEAAITILRIDDLIKL-KE
Caenorhabditis    IPQLQHLKWAGLDLEEGTIRDNKEAGILEPALSKVKSLKFATEAAITILRIDDLIKL---
Drosophila        KPERSDLKWTGLDLIEGVVRDNKKAGVLEPAMSKIKSLKFATEAAITILRIDDMIKLNPE
Mus               NPERKNLKWIGLDLVHGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIKLHPE
Homo              NPERKNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIKLHPE

Arabidopsis       VKDESQ-GEE----------
Schistosoma       EKQPDHDGDECGY-------
Caenorhabditis    DKQEPLGGDDCHA-------
Drosophila        DKSGKSYADACAA--GELDG
Mus               SKDDKHGSYENAVHSGALDD
Homo              ILRIKHGSYEDAVHSGALND

[Triose phosphate isomerase]

Arabidopsis       M--ARKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRS
Schistosoma       MSGSRKFFVGGNWKMNGSRDDNDKLLKLLSEAHFDDN--TEVLIAPPSVFLHEIRKSLKK
Caenorhabditis    M--TRKFFVGGNWKMNGDYASVDGIVTFLNASADNSS--VDVVVAPPAPYLAYAKSKLKA
Drosophila        M--SRKFCVGGNWKMNGDQKSIAEIAKTLSSAALDPN--TEVVIGCPAIYLMYARNLLPC
Mus               MAPTRKFFVGGNWKMNGRKKCLGELICTLNAANVPAG--TEVVCAPPTAYIDFARQKLDP
Homo              MAPSRKFFVGGNWKMNGRKQSLGELIGTLNAAKVPAD--TEVVCAPPTAYIDFARQKLDP

Arabidopsis       DFFVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYAL
Schistosoma       EIHVAAQNCYKVSKGAFTGEISPAMIRDIGCDWVILGHSERRNIFGESDELIAEKVQHAL
Caenorhabditis    GVLVAAQNCYKVPKGAFTGEISPAMIKDLGLEWVILGHSERRHVFGESDALIAEKTVHAL
Drosophila        ELGLAGQNAYKVAKGAFTGEISPAMLKDIGADWVILGHSERRAIFGESDALIAEKAEHAL
Mus               KIAVAAQNCYKVTNGPFTGEISPGMIKDLGATWVVLGHSERRHVFGESDELIGQKVSHAL
Homo              KIAVAAQNCYKVTNGAFTGEISPGMIKDCGATWVVLGHSERRHVFGESDELIGQKVAHAL

Arabidopsis       AQGLKVIACVGETLEEREAGSTMDVVAAQTKAIADRVT---NWSNVVIAYEPVWAIGTGK
Schistosoma       AEGLSVIACIGETLSERESNKTEEVCVRQLKAIANKIKSADEWKRVVVAYEPVWAIGTGK
Caenorhabditis    EAGIKVVFCIGEKLEEREAGHTKDVNFRQLQAIVDKGV---SWENIVIAYEPVWAIGTGK
Drosophila        AEGLKVIACIGETLEEREAGKTNEVVARQMCAYAQKIK---DWKNVVVAYEPVWAIGTGK
Mus               AEGLGVIACIGEKLDEREAGITEKVVFEQTKVIADNVK---DWSKVVLAYEPVWAIGTGK
Homo              AEGLGVIACIGEKLDEREAGITEKVVFEQTKVIADNVK---DWSKVVLAYEPVWAIGTGK

Arabidopsis       VASPAQAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGA
Schistosoma       VATPQQAQEVHNFLRKWFKTNAPNGVDEKIRIIYGGSVTAANCKELAQQHDVDGFLVGGA
Caenorhabditis    TASGEQAQEVHEWIRAFLKEKVSPAVADATRIIYGGSVTADNAADVGKKPDIDGFLVGGA
Drosophila        TATPDQAQEVHASLRQWLSDNISKEVSASLRIQYGGSVTAANAKELAKKPDIDGFLVGGA
Mus               TATPQQAQEVHEKLRGWLKSNVNDGVAQSTRIIYGGSVTGATCKELATPADVDGFLVGGA
Homo              TATPQQAQEVHEKLRGWLKSNVSDAVAQSTRIIYGGSVTGATCKELASQPDVDGFLVGGA

Arabidopsis       SLKPEFIDIIKAAEVNKSA
Schistosoma       SLKPEFTEICKARQR----
Caenorhabditis    SLKPDFVKIINARS-----
Drosophila        SLKPEFLDIINARQ-----
Mus               SLKPEFVDIINAKQ-----
Homo              SLKPEFVDIINAKQ-----

;
END;


begin assumptions;
exset *saved = 1-15 64-73 169-173 239-254 344-402 407-415 424-431 445-453 509-510 
	   558-579 603-610 711-788 1004-1019 1237-1244 1253-1261 1289-1292 1312-1319 1338-1346
	   1355-1358 1364-1368 1518-1523 1530-1535 1570-1583 1702-1771 1784-1796 1801-1814
	   1826-1844 1883-1887 1897-1899 1914-1921 1970 2102-2855 2929-2930 2966-2978 3005-3020 
	   3055-3143 3157-3163 3185-3186 3199-3203 3259-3278 3308-3317 3378-3384 3428-3436 
	   3546-3558 3710-3723 3738-3785 3953-3966 4311-4337 4363-4374 4483-4495 4586-4592 ;
endblock;