Difference between revisions of "Evo Devo Fall2013"

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(Week 1 (Aug. 27/29): Overview of evolutionary developmental biology (EJ))
(Week 1 (Aug. 27/29): Overview of evolutionary developmental biology (EJ))
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<li>Wray GA. 2010. Embryos and evolution: 150 years of reciprocal illumination.  Pp. 215-239 In Bell MA, Futuyma DJ, Eanes WF, Levinton JS, Evolution since Darwin: The First 150 Years. Sinauer Associates, Sunderland MA. [EJ will provide copies]</li>
 
<li>Wray GA. 2010. Embryos and evolution: 150 years of reciprocal illumination.  Pp. 215-239 In Bell MA, Futuyma DJ, Eanes WF, Levinton JS, Evolution since Darwin: The First 150 Years. Sinauer Associates, Sunderland MA. [EJ will provide copies]</li>
 
If time permits (I know there's not much this week!), I'd also encourage you to read this:
 
If time permits (I know there's not much this week!), I'd also encourage you to read this:
<li>Müller GB. 2007. Evo-devo: extending the evolutionary synthesis. Nat Rev Genet. 8(12):943-9. [http://ezproxy.lib.uconn.edu/login?url=http://www.nature.com/nrg/journal/v8/n12/full/nrg2219.html]</li>
+
<li>Müller GB. 2007. Evo-devo: extending the evolutionary synthesis. Nat Rev Genet. 8(12):943-9. [http://ezproxy.lib.uconn.edu/login?url=http://www.nature.com/nrg/journal/v8/n12/full/nrg2219.html link]</li>
 
</ul>
 
</ul>
 
Discussion Questions:<br>
 
Discussion Questions:<br>

Revision as of 01:47, 27 August 2013

EEB 5333, Fall 2013
Evolutionary Developmental Biology
Meeting Time: Tuesdays and Thursdays, 2:00-3:15 pm, Bamford Room (TLS 171B)

Description

This is an advanced course that explores the interface between evolutionary biology and developmental biology. In addition to considering how developmental pathways evolve, and the developmental basis of phenotypic evolution, we will ask what novel insights emerge from a synthesis of these fields. Major topics to be considered include the following: developmental constraints, homology, plasticity, novelty and evolvability.

Instructors

Dr. Elizabeth Jockusch
Office: Biology/Pharmacy 305B
Phone: (860) 486-4452
Office hours: by appointment

Dr. Carl Schlichting
Office: Torrey Life Sciences 366
Phone: (860) 486-4056
Office hours: by appointment


Announcements and Handouts

Books & Sources in Evolutionary Developmental Biology


Expectations and Grading

This course has a mixed lecture/discussion format. In general, Tuesdays will be used for lectures that provide an overview and background information. Thursdays will be dedicated to student-led discussion based on reading from the literature. We expect everyone to participate actively in the class. In order to help prepare for discussions, you should write a brief (<1 page) reaction piece to each set of readings, highlighting your thoughts about the readings, connections between them or questions raised by them. This will be handed in each week. Responsibility for leading the discussions will rotate. 
 You are expected to complete an independent project on a topic of your choice. Ideally, your topic will be closely connected to your own research interests, and also integrate multiple topics covered in class . You should discuss your choice of topics with one of us no later than Friday, October 4. To help you stay on track, an outline and relevant references are due on Tuesday, Nov. 12. The final project paper is due Tuesday, Dec. 3, and the last week of class will be devoted to presentations and discussions based on these projects. There will be one take-home exam due the day of the Final Exam. It will consist of one or several essay questions that will ask you to integrate the knowledge that you have acquired during the course. 



Deadlines

WeeklyDiscussion pieces
Friday, Oct. 4Independent project topic approved
Tuesday, Nov. 12Independent project outline and references due
Tuesday, Dec. 3Independent project paper due
Dec. 3-5Independent project presentations
Tuesday, Dec. 10Final exam due


Course grade

Discussions35%, including participation, leading discussion, and reaction pieces
Independent project40%, based on presentation (15%) and paper (25%)
Final exam25%


Topics and Readings

Week 1 (Aug. 27/29): Overview of evolutionary developmental biology (EJ)

Discussion Leader: Elizabeth
Discussion Readings:

  • Moczek AP. 2012. The nature of nurture and the future of evodevo: toward a theory of developmental evolution. Int. Comp. Biol. 52:108-119. link
  • Wray GA. 2010. Embryos and evolution: 150 years of reciprocal illumination. Pp. 215-239 In Bell MA, Futuyma DJ, Eanes WF, Levinton JS, Evolution since Darwin: The First 150 Years. Sinauer Associates, Sunderland MA. [EJ will provide copies]
  • If time permits (I know there's not much this week!), I'd also encourage you to read this:

  • Müller GB. 2007. Evo-devo: extending the evolutionary synthesis. Nat Rev Genet. 8(12):943-9. link

Discussion Questions:

Week 2 (Sept. 3/5): Morphological and molecular patterns (EJ)

Discussion Leader:
Discussion Readings: The developmental hourglass and the phylotypic stage
Discussion Questions:

Week 3 (Sept. 10/12): The molecular building blocks of development (CS)

Discussion Leader:
Discussion Readings:
Discussion Questions:

Week 4 (Sept. 17/19): Evolution of developmental networks (CS)

Discussion Leader:
Discussion Readings:
Discussion Questions:

Week 5 (Sept. 24/26): Homology (CS)

Discussion Leader:
Discussion Readings:
Discussion Questions:

Week 6 (Oct. 1/3): Homoplasy (CS)

Discussion Leader:
Discussion Readings:
Discussion Questions:

Week 7 (Oct. 8/10): Constraints (EJ)

Discussion Leader:
Discussion Readings:
Discussion Questions:

Week 8 (Oct. 15/17): Novelty (EJ)

Discussion Leader:
Discussion Readings:
Discussion Questions:

Week 9 (Oct. 22/24): Morphospace (CS)

Discussion Leader:
Discussion Readings:
Discussion Questions:

Week 10 (Oct. 29/31): Modularity (EJ)

Discussion Leader:
Discussion Readings:
Discussion Questions:

Week 11 (Nov. 5/7): Robustness and plasticity (CS)

Discussion Leader:
Discussion Readings:
Discussion Questions:

Week 12 (Nov. 12/14): Evolvability (EJ)

Discussion Leader:
Discussion Readings:
Discussion Questions:

Week 13 (Nov. 19/21): Case studies (CS/EJ)

Discussion Leader:
Discussion Readings:
Discussion Questions:

Week 14 (Nov. 26/28): Happy Thanksgiving!

Week 15 (Dec. 3/5): Project Presentations