Difference between revisions of "Evo Devo Fall2011"

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(Topics and Readings)
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'''Aug. 30-Sept 1:  Overview of evolutionary developmental biology'''
 
'''Aug. 30-Sept 1:  Overview of evolutionary developmental biology'''
  
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Discussion Readings<br>
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<li>Brakefield PM. 2011. Evodevo and accounting for Darwin's endless forms.  Philos Trans R Soc Lond B Biol Sci. 366: 2069-75 [http://www.nature.com/nrg/journal/v8/n12/full/nrg2219.html link]</li>
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<li>Müller GB. 2007. Evo-devo: extending the evolutionary synthesis. Nat Rev Genet. 8(12):943-9 [http://rstb.royalsocietypublishing.org/content/366/1574/2069.long link]</li>
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<li>Wray GA. 2010. Embryos and evolution: 150 years of reciprocal illumination.  Pp. 215-239 In Bell MA, Futuyma DJ, Eanes WF, Levinton JS, Evolution since Darwin: The First 150 Years. Sinauer Associates, Sunderland MA. [will be distributed in lecture]</li>
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'''Sept. 6-8:  The molecular building blocks of development'''
 
'''Sept. 6-8:  The molecular building blocks of development'''
  
 
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'''Sept. 13-15:  Novelty at the molecular level'''
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'''Sept. 13-15:  RNAi silencing and other mechanisms of gene regulation'''
  
 
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'''Sept. 20-22:  Morphological novelty'''
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'''Sept. 20-22:  Development and homoplasy'''
  
 
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'''Sept. 27-29: Development and homoplasy'''
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'''Sept. 27-29: Development and homology '''
  
 
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'''Oct. 4-6:  Development and homology'''
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'''Oct. 4-6:  Evolution of developmental networks'''
  
 
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'''Oct. 18-20: Evolution of developmental pathways'''
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'''Oct. 18-20: Developmental modules '''
  
 
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'''Oct. 25-27: Developmental network structure'''
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'''Oct. 25-27: Robustness and canalization '''
  
 
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'''Nov. 2-4:  RNAi silencing and other mechanisms of gene regulation'''
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'''Nov. 2-4:  Evolvability'''
  
 
<br>
 
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'''Nov. 9-11:  Developmental modules'''
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'''Nov. 9-11:  Novelty'''
  
 
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'''Nov. 16-18: Evolvability'''
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'''Nov. 16-18: Morphospace'''
  
 
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'''Nov. 29-Dec. 1: TBD'''
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'''Nov. 29-Dec. 1: EcoEvoDevo'''
  
 
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'''Dec. 6-8:  Project presentations'''
 
'''Dec. 6-8:  Project presentations'''
 
Other ideas:  genomic perspectives; morphospace, plasticity, eco-evo-devo
 

Revision as of 21:09, 29 August 2011

EEB 5333, Fall 2011
Evolutionary Developmental Biology
Meeting Time: Tuesdays and Thursdays, 2-3:15 pm in TLS 301

Description

This is an advanced course that explores the interface between evolutionary biology and developmental biology. In addition to considering how developmental pathways evolve, and the developmental basis of phenotypic evolution, we will ask what novel insights emerge from a synthesis of these fields. Major topics to be considered include the following: developmental constraints, homology, plasticity, novelty and evolvability.

Instructors

Dr. Elizabeth Jockusch
Office: Biology/Pharmacy 305B
Phone: (860) 486-4452
Office hours: by appointment

Dr. Carl Schlichting
Office: Torrey Life Sciences 366
Phone: (860) 486-4056
Office hours: by appointment


Format

This course has a mixed lecture/discussion format. In general, Tuesdays will be used for lectures that provide an overview and background information. Thursdays will be dedicated to student-led discussion based on reading from the literature.

Expectations and Grading

We expect everyone to participate actively in the class. In order to help prepare for discussions, you should write a brief (<1 page) reaction piece to each set of readings, highlighting your thoughts about the readings, connections between them or questions raised by them. This will be handed in each week. Responsibility for leading the discussions will rotate. 
 You are required to complete an independent project on a topic of your choice. Appropriate topics will integrate diverse data types or theoretical models and empirical information, and allow you to explore a particular example or concept in greater depth. You should discuss your choice of topics with one of us no later than Friday, October 28. The last week of class will be devoted to presentations and discussions based on these projects. You will be in charge of assigning a paper relevant to your presentation.
 There will be one take-home exam due the day of the Final Exam. It will consist of one or several essay questions that will ask you to integrate the knowledge that you have acquired during the course. 



Deadlines

WeeklyDiscussion pieces Friday, Oct. 28Term paper topic approved
Thursday, Dec. 1Independent project paper due
Dec. 6-8Independent project presentations
Tuesday, Dec. 13Final exam due


Course grade

Discussions35%, including participation, leading discussion, and reaction pieces
Individual project40%, based on presentation (15%) and paper (25%)
Final exam25%


Topics and Readings

Aug. 30-Sept 1: Overview of evolutionary developmental biology


Discussion Readings

  • Brakefield PM. 2011. Evodevo and accounting for Darwin's endless forms. Philos Trans R Soc Lond B Biol Sci. 366: 2069-75 link
  • Müller GB. 2007. Evo-devo: extending the evolutionary synthesis. Nat Rev Genet. 8(12):943-9 link
  • Wray GA. 2010. Embryos and evolution: 150 years of reciprocal illumination. Pp. 215-239 In Bell MA, Futuyma DJ, Eanes WF, Levinton JS, Evolution since Darwin: The First 150 Years. Sinauer Associates, Sunderland MA. [will be distributed in lecture]

Sept. 6-8: The molecular building blocks of development


Sept. 13-15: RNAi silencing and other mechanisms of gene regulation


Sept. 20-22: Development and homoplasy


Sept. 27-29: Development and homology


Oct. 4-6: Evolution of developmental networks


Oct. 11-13: Developmental constraints and evolution


Oct. 18-20: Developmental modules


Oct. 25-27: Robustness and canalization


Nov. 2-4: Evolvability


Nov. 9-11: Novelty


Nov. 16-18: Morphospace


Nov. 22-24: Thanksgiving Break


Nov. 29-Dec. 1: EcoEvoDevo


Dec. 6-8: Project presentations