EEB 3895 Medical Parasitology Fall 2016
EEB 3895 Medical Parasitology Fall 2016
Course description: Parasitic agents of human disease: protozoan, helminth, and arthropod parasites of medical importance and their basic morphology, classification, and life-cycles; diagnosis of infection; current topics in parasitic diseases.
Format : Class periods will include a blend of lectures and group activities.
Prerequisites: Three credits of introductory biology or approval of instructor.
Required text: Foundations of Parasitology 8th (2008; Roberts & Janovy) or 9th (2012; Roberts, Janovy & Nadler) edition; McGraw Hill.
Lecture: Mondays and Wednesdays, 9:05–10:20 am; Where: TLS Rm. 301
Professor: Dr. J.N. Caira
office: TLS 483 (office hours by arrangement)
email: Dr. Janine N. Caira
The course is focused on the biology of the parasites responsible for human diseases. It is organized by parasite group and aims to provide:
(1) an overview of the major parasite taxa infecting humans globally,
(2) an appreciation of the diversity of life-cycles, portals of entry, sites infected, modes of reproduction these parasites employ, and
(3) a basic understanding of the pathology associated with, and diagnosis of, infection with each major parasite group.
Specific Learning Outcomes
The course will provide a sound parasitological foundation for students who wish to pursue a career in a medical or related academic field.
(1) Know fundamental concepts of parasitology and the technical vocabulary used in the field.
(2) Identify common human parasite taxa based on morphological, biological, clinical, and geographic criteria, and the diseases they cause.
(3) Understand the human body as a home to parasites in terms of portals of entry and exit, and sites occupied by parasites.
(4) Appreciate the complexity of parasite life-cycles and transmission strategies.
(5) Hone critical thinking skills by applying fact-based knowledge of human parasites to scenarios involving infection diagnosis and prevention.
|3 Lecture Exams (90 points each)||270 points|
|Final Comprehensive Essay Exam||100 points|
|Class Participation (see * below)||30 points|
|TOTAL POSSIBLE POINTS:||400 points|
http://asp.unl.edu -The American Society of Parasitologists (general parasitology)
http://www.astmh.org -The American Society of Tropical Medicine and Hygiene (medical parasitology)
http://www.dpd.cdc.gov -Center for Disease Control (CDC) resource for identification of parasitic disease agents (US government infectious diseases surveillance agency; focused on human and zoonotic parasites)
http://www.who.int/neglected_diseases/diseases/en/ -World Health Organization (WHO) Programme on neglected tropical diseases (Note that 11 of the 17 targeted diseases deemed important globally are caused by parasitic organisms!)
http://www.who.int/topics/malaria/en/ -WHO Global Malaria Programme focusing on prevention, treatment and control of this protist infection
This schedule is subject to change. Check regularly for updates!
|In-class Activity*||Class Period||Topic||Readings |
9th edition (8th edition)
|M Aug 29||Introduction; General Concepts of Parasitology||Ch 1 & 2 (both eds.)|
|E1||W Aug 31||The human body as a home to parasites; CDC & WHO|
|M Sep 05||Labor Day (no class)|
|W Sep 07||Introduction to zoonotic infections; Giardia: Giardiasis; Naegleria: PAM||88–92 (90–94); 116–119 (114–117)|
|M Sep 12||Entamoeba: Amoebiasis; Trichomoniasis||107–115 (105–113); 95–99 (93–97)|
|E2||W Sep 14||Trypanosoma: African Trypanosomiasis (Sleeping sickness)||61–70 (both eds.)|
|M Sep 19||Trypanosoma: American Trypanosomiasis (Chagas disease)||71–75 (71–76)|
|E3||W Sep 21||Leishmania: Leishmaniasis||77–85 (both eds.)|
Dr. Mary Ann McDowell (Leishmaniasis)
University of Notre Dame
|M Sep 26||Plasmodium: Malaria||147–164 (143–159) & colour plates|
|W Sep 28||Plasmodium: Malaria||147–164 (143–159) & colour plates|
|M Oct 3||Exam I (Covers material up to end of Sept 28th)|
|E4||W Oct 5||Toxoplasma: Toxoplasmosis and related diseases||133–140 (131–137)|
|M Oct 10||Cryptosporidium: Cryptosporidiosis and related diseases||141–144 (122–123 & 140–141)|
|E5||W Oct 12||Liver flukes: Fasciolosis; Clonorchiasis||Ch 15 (both eds.); 268–273 (256–261); 287–292 (275–280)|
|M Oct 17||Lung flukes: Paragonimosis||281–285 (269–273)|
Dr. Kevin Lafferty
University of California-Santa Barbara
Dr. Lafferty interview
|W Oct 19||Blood flukes: Schistosomiasis||249–262 (237–250)|
Dr. Patrick Skelly
|M Oct 24||Blood flukes: Schistosomiasis||249–262 (237–250)|
|E6||W Oct 26||Tapeworms: Cysticercosis; Taeniasis||Ch 20 (both eds.); 346–351 (330–335); 355–357 (340–341)|
Dr. Peter Olson
(cestodes & cancer)
British Museum of Natural History
Hymenolepis nana 2015 NEJM
|M Oct 31||Tapeworms: Echinococcosis; Diphyllobothriasis||351–355 (335–339); 341–345 (325–329)|
|W Nov 2||Exam II (Covers material from Oct 5th through Oct 31st)|
Dr. Roman Kuchta
Czech Academy of Sciencies
|M Nov 7||Nematodes: Ascariasis; Toxocarosis||Ch 22 (both eds.); 433–442 (411–421)|
|E7||W Nov 9||Nematodes: pinworms, Hookworm disease||447–450 (425–429); 419–426 (397–405)|
Dr. John Hawdon
George Washington University
|M Nov 14||Nematodes: Filariasis; Dracunculiasis||463–474 (441–453); 479–484 (457–462)|
|E8||W Nov 16||Nematodes: Trichinosis; Trichuriasis||399–409 (377–388)|
|M Nov 21||Thanksgiving (no class)|
|W Nov 23||Thanksgiving (no class)|
Dr. William Campbell
Merck (retired); 2016 Nobel Laureate
|M Nov 28||Mites, ticks, and tick-borne diseases||639–645 (611–616); 653–655 (625–629)|
|E9||W Nov 30||Fleas, lice, flies and bed bugs||589–599 (563–573); 569–579 (543–554); 583–584 (557–559)|
Dr. Dale Clayton
University of Utah
|M Dec 5||Human parasites and climate change|
|E10||W Dec 7||General considerations|
|Tentative date|| M Dec 12
|Exam III (Covers Nov 7th through Dec 7th) & Final (Comprehensive Essays)|